Call Now! 866-415-6313

4.8 Rating | 5,000+ Clients Treated Since 2016

Table of Contents

What is the M367 Hydrocodone-Acetaminophen Pill? | What You Need to Know

The M367 white oval pill

Clinically Reviewed by: Charee Marquez, LMFT

In the realm of pain management, hydrocodone-based medications like M367 pills (hydrocodone bitartrate and acetaminophen) play a pivotal role. These opioid analgesics are prescribed for treating moderate to moderately severe pain, offering much-needed relief to individuals grappling with chronic pain conditions or recovering from surgery. However, their potency comes with a set of considerations, from potential adverse reactions to the risk of addiction and overdose. Understanding the dynamics of opioid drugs and their interaction with the body is paramount, especially in light of the opioid epidemic sweeping across nations. This blog aims to delve into the nuances of hydrocodone medications, exploring their benefits, risks, and the critical role of healthcare providers in ensuring safe usage and mitigating harm.

What is the M367 Pill?

M367 is an imprint on a white, capsule-shaped pill. It is commonly associated with a combination pain medication containing 325 milligrams of acetaminophen and 10 milligrams of hydrocodone bitartrate. Hydrocodone is an opioid pain reliever, and acetaminophen is a non-opioid pain reliever and fever reducer.

Composition of M367 Pills

  • Hydrocodone Bitartrate: M367 pills contain hydrocodone, an opioid painkiller known for its efficacy in alleviating moderate to severe pain. As an opioid, hydrocodone interacts with the brain’s receptors, altering the perception of pain.

  • Acetaminophen: The other active ingredient in M367 pills is acetaminophen, a non-narcotic painkiller and fever reducer. Acetaminophen works by inhibiting certain enzymes in the brain, contributing to pain relief and reducing fever.

Understanding Hydrocodone Bitartrate and Acetaminophen in M367 Pills

Acetaminophen and hydrocodone bitartrate are two medications commonly combined in prescription pain-relief medications, such as the M 367 pill. Here’s an overview of each:

1. Acetaminophen (Tylenol):

  • Acetaminophen is a widely used over-the-counter (OTC) medication known for its pain-relieving (analgesic) and fever-reducing (antipyretic) properties.
  • It works by inhibiting the production of prostaglandins, chemicals in the body that promote pain and fever.
  • Acetaminophen is commonly used to relieve mild to moderate pain, such as headaches, muscle aches, menstrual cramps, and toothaches.
  • It’s considered relatively safe when taken at recommended doses, but excessive use can lead to liver damage or failure.

2. Hydrocodone bitartrate:

  • Hydrocodone is a semi-synthetic opioid analgesic derived from codeine, commonly used to manage moderate to severe pain.
  • It works by binding to opioid receptors in the brain and spinal cord, reducing the perception of pain and producing feelings of relaxation and euphoria.
  • Hydrocodone is often combined with other medications, such as acetaminophen or ibuprofen, to enhance its pain-relieving effects.
  • Like other opioids, hydrocodone has a high potential for abuse, addiction, and dependence, and should only be used under the supervision of a healthcare professional and according to the prescribed dosage and duration.

In combination, acetaminophen and hydrocodone bitartrate work synergistically to provide more effective pain relief than either medication alone. This combination is commonly used to manage moderate to severe pain, such as after surgery, injury, or for chronic pain conditions.


M367 Pill Imprints

The pill with the imprint M367 is white, capsule-shaped, and has been identified as Acetaminophen and Hydrocodone Bitartrate 325 mg / 10 mg. It is supplied by Mallinckrodt Pharmaceuticals. Hydrocodone is an opioid pain medication, and acetaminophen is a non-opioid pain reliever.

Common brand names for medications containing hydrocodone and acetaminophen include:

Nomenclature Variations

  • White M367 Pill: The most common identifier for these tablets is the characteristic white color and the alphanumeric imprint “M367” etched on each pill.

  • Hydrocodone M367: Another commonly used term, highlighting the inclusion of hydrocodone bitartrate as a key component in the medication.

In various settings and regions, the pill with the imprint M367 may go by different names that might ring a bell. Being aware of these names can be valuable for individuals or their loved ones to identify the drug and understand its usage.

M367 Pill Brands and Nicknames

Recognizable Brands:

  1. Norco
  2. Vicodin
  3. Lortab
  4. Hydrocet
  5. Zydone
  6. Xodol
  7. Lorcet

Street Names:

  • “Vikes”
  • “Hydros”
  • “Loris”
  • “Watsons”
  • “Tabs”
  • “Happy Pills”
  • “367s”

Understanding the various monikers and brand names associated with this medication is crucial for promoting awareness and responsible usage. Always ensure that prescription medications are taken as directed by a healthcare professional to avoid potential health risks and complications.

M367 Pill Controlled Substance Classification

The M367 pill is classified as a Schedule II/IIN controlled substance. This classification is based on the presence of hydrocodone, one of its active ingredients. The controlled substance schedules are established by the U.S. Drug Enforcement Administration (DEA) to regulate substances based on their potential for abuse, medical use, and the degree of dependence they may cause.

In Schedule II, substances have a high potential for abuse, accepted medical uses with severe restrictions, and the likelihood of severe psychological or physical dependence. Hydrocodone, an opioid analgesic found in the M367 pill, is considered highly addictive, contributing to its Schedule II classification.

Here are some key points about Schedule II controlled substances:

  1. Prescription Requirement: Schedule II substances, including hydrocodone-containing medications like the M367 pill, can only be legally obtained with a written prescription from a licensed healthcare provider.

  2. Prescription Refills: Unlike medications in lower schedules, Schedule II medications generally have more stringent regulations regarding prescription refills. Healthcare providers often need to issue a new prescription for each supply.

  3. Age Restrictions: Controlled substances in Schedule II are typically prescribed only to individuals 18 years of age and older.

  4. ID Verification: Pharmacies may require proof of identification, such as a government-issued ID, when dispensing Schedule II medications.


M367 Pill Types and Dosages

The M367 pill is a white, capsule-shaped tablet with the imprint “M367.” It is a combination medication that contains two active ingredients: hydrocodone bitartrate and acetaminophen. Here are the specific types and dosages of each component in the M367 pill:

  1. Hydrocodone Bitartrate:

    • Hydrocodone is an opioid analgesic, commonly used for pain relief.
    • The M367 pill contains 10 mg of hydrocodone bitartrate.
  2. Acetaminophen:

    • Acetaminophen is a non-opioid pain reliever and fever reducer.
    • The M367 pill contains 325 mg of acetaminophen.

M367 Pill Dosage Guidelines

The M367 pill is an oval, white tablet with the imprint “M367,” and it contains a combination of two pain-relieving medications: 325 mg of acetaminophen (Tylenol) and 10 mg of hydrocodone, which is an opioid analgesic.

Dosage guidelines for medications containing hydrocodone should be strictly followed according to the prescription provided by your healthcare provider. The typical dosing regimen for M367 or similar hydrocodone-containing medications is as follows:

Standard Dosage:

  • Adults: One tablet (M367) every 4 to 6 hours as needed for pain.
  • The total daily dosage should not exceed the recommended limit, and the frequency and dosage may be adjusted based on individual pain response.

Important Considerations:

  1. Individual Variation: Dosage requirements may vary among individuals. Your healthcare provider will determine the appropriate dose based on factors such as your pain severity, medical history, and response to the medication.

  2. Avoiding Excessive Use: It’s crucial not to exceed the recommended dosage or take the medication more frequently than prescribed. Excessive use can lead to serious health risks, including liver damage from the acetaminophen component or opioid-related side effects.

  3. Short-Term Use: Hydrocodone-containing medications are typically prescribed for short-term use to manage acute pain. Prolonged use can lead to tolerance, dependence, and an increased risk of side effects.

  4. Follow Healthcare Provider’s Guidance: Always follow your healthcare provider’s instructions and consult them if you have any questions or concerns about the dosage, side effects, or overall use of the medication.

M367 Pill Efficacy

The efficacy of the M367 pill, or any medication containing hydrocodone and acetaminophen (such as Vicodin), lies in its ability to manage pain. Hydrocodone is an opioid analgesic, while acetaminophen is a non-opioid pain reliever and fever reducer. The combination is often prescribed for the short-term management of moderate to severe pain.

The efficacy of this medication is influenced by several factors:

  1. Pain Severity: The M367 pill is typically prescribed for pain management, especially in cases where non-opioid medications may be insufficient. Its effectiveness depends on the severity and nature of the pain being treated.

  2. Individual Response: Responses to pain medications can vary among individuals. Factors such as the individual’s overall health, tolerance, and specific pain condition play a role in how well the medication works.

  3. Proper Use: Following the prescribed dosage and instructions is crucial for maximizing efficacy and minimizing the risk of side effects. Taking the medication as directed by your healthcare provider is essential.

  4. Short-Term Use: Hydrocodone-containing medications are generally intended for short-term use due to the risk of developing tolerance, dependence, and potential side effects associated with opioids.

How Long Does the M367  Pill Stay in Your System?

The M367 pill is a combination medication containing hydrocodone bitartrate (10 mg) and acetaminophen (325 mg). Hydrocodone is an opioid analgesic, and acetaminophen is a pain reliever and fever reducer. The half-life of each component can vary.

The half-life of hydrocodone is approximately 3 to 4 hours on average. This means that it takes about 3 to 4 hours for half of the hydrocodone to be eliminated from the body. Individual variations can occur, influenced by factors such as age, liver function, and other medications being taken.

Acetaminophen has a shorter half-life, typically around 2 to 3 hours. It is primarily metabolized by the liver, and the elimination process can be influenced by liver function and other factors.

It’s important to note that the combination of hydrocodone and acetaminophen in the M367 pill means that both substances will be present in the body and contribute to the overall effects and duration of action.

M367 Pill Onset and Duration

The M367 pill is a white, capsule-shaped tablet with the imprint “M367.” It contains a combination of hydrocodone bitartrate (10 mg) and acetaminophen (325 mg). Hydrocodone is an opioid analgesic, and acetaminophen is a pain reliever and fever reducer.

Here are general guidelines for the onset and duration of effects of the M367 pill:

  1. Onset of Effects:

    • Hydrocodone, the opioid component in the M367 pill, typically begins to take effect within about 30 minutes to an hour after ingestion. Individuals may start to experience pain relief during this time frame.
    • Acetaminophen, the other component in the pill, also contributes to pain relief and has a relatively rapid onset, generally within 30 to 60 minutes.
  2. Duration of Effects:

    • The duration of action for hydrocodone is generally around 4 to 6 hours. This means that the pain-relieving effects of the medication may last for this period before another dose is needed.
    • Acetaminophen has a shorter duration of action, typically around 4 to 6 hours as well.

It’s important to note that these are general estimates, and individual responses to the medication may vary. The onset and duration can be influenced by factors such as the individual’s metabolism, overall health, and the presence of other medications.

How Long is the M367 Pill Detectable in Your System?

The detectability of hydrocodone, the opioid component in the M367 pill, in drug tests can depend on various factors, including the type of test used, the individual’s metabolism, and the time elapsed since the last dose. Additionally, the detectability of acetaminophen (present in the M367 pill) is generally not assessed in standard drug tests.

Here are some general guidelines for the detectability of hydrocodone:

  1. Urine Test:

    • Hydrocodone is typically detectable in urine for about 2 to 4 days after the last dose. However, this timeframe can vary based on factors such as individual metabolism, hydration status, and the specific testing method.
  2. Blood Test:

    • Hydrocodone can be detected in blood for approximately 24 hours after ingestion.
  3. Saliva Test:

    • Hydrocodone can be detectable in saliva for up to 1 to 4 days.
  4. Hair Follicle Test:

    • Hydrocodone may be detectable in hair follicles for a more extended period, potentially up to 90 days or even longer.

It’s important to note that drug testing results can vary, and the above estimates are general guidelines. Detection times can be influenced by individual factors, such as metabolism, liver function, and hydration.

M367 Pill Storage and Disposal


  • Store the M367 pill in a cool, dry place away from direct sunlight.
  • Keep the medication in its original packaging or container, and ensure the lid is tightly closed.
  • Store the medication out of reach of children and pets.


  • Dispose of expired or unused medication properly to prevent accidental ingestion or environmental contamination.
  • Follow local regulations for medication disposal or use designated drug take-back programs in your community.
  • Do not flush medications down the toilet unless explicitly instructed to do so.
  • If no take-back programs are available, mix the medication with an undesirable substance (like coffee grounds or cat litter) and place it in a sealed bag before throwing it in the trash.
  • Remove any personal information from the medication packaging before disposal.

M 367 Pill Precautions

Before taking M367, it’s important to consider several precautions:

  1. Follow your doctor’s prescription carefully and do not exceed the recommended dosage.
  2. Inform your doctor about any other medications, supplements, or herbal remedies you are taking, especially other opioids, sedatives, tranquilizers, or alcohol.
  3. Avoid drinking alcohol while taking M367, as it can increase the risk of side effects and liver damage.
  4. Be cautious when operating machinery or driving, as M367 may cause drowsiness or dizziness.
  5. Do not crush, chew, or break the pill. Swallow it whole with a full glass of water.
  6. Inform your doctor if you have a history of substance abuse, respiratory problems, liver or kidney disease, or any other medical conditions.
  7. Store M367 securely and out of reach of children and pets.
  8. Never share M367 with others, especially those with a history of drug abuse or addiction.

Following these precautions can help ensure the safe and effective use of M367. If you have any concerns or questions, consult your healthcare provider.

M367 Pill Uses as an Opioid Pain Reliever

he M367 pill is a prescription medication containing a combination of two active ingredients: hydrocodone bitartrate and acetaminophen. It is primarily used for the management of moderate to moderately severe pain. Here are the main uses of the M367 pill:

  1. Pain Relief: The M367 pill is prescribed to alleviate pain that ranges from moderate to moderately severe. It is commonly used to manage pain associated with conditions such as dental procedures, injuries, surgeries, musculoskeletal pain, and other medical conditions where over-the-counter pain relievers may not provide sufficient relief.

  2. Postoperative Pain: After surgical procedures, the M367 pill may be prescribed to help manage postoperative pain. It can provide effective pain relief during the recovery period, allowing patients to rest comfortably and engage in activities essential for healing.

  3. Chronic Pain: In some cases, the M367 pill may be prescribed for the management of chronic pain conditions, such as osteoarthritis, rheumatoid arthritis, or chronic back pain. However, its use for chronic pain is typically limited to short-term or intermittent use due to the risk of tolerance, dependence, and other adverse effects associated with long-term opioid use.

  4. Pain Management in Palliative Care: The M367 pill may be used as part of pain management in palliative care for individuals with terminal illnesses or advanced stages of disease. It can help improve the quality of life by providing relief from pain and promoting comfort in patients nearing the end of life.

Additionally, it’s important to consider the potential impact of opioid use, including M367, on mental health. Opioids can exacerbate pre-existing mental health disorders such as depression, anxiety, bipolar disorder, and schizophrenia. Furthermore, the use of opioids may contribute to the development of new mental health issues, including depression and anxiety, especially in individuals with a history of substance abuse.

It’s essential to use the M367 pill exactly as prescribed by a healthcare professional and to follow dosage instructions carefully.


Therapeutic Role in Pain Management

  • Opioid Analgesics: M367 pills fall under the category of opioid analgesics, a class of medications recognized for their potent pain-relieving properties. The combination of hydrocodone bitartrate and acetaminophen within M367 contributes to their efficacy in managing a wide range of pain intensities.

  • Moderate to Severe Pain: Tailored for addressing moderate to severe pain levels, M367 pills serve as a valuable resource for individuals navigating the challenges of acute or chronic pain conditions.

Prevalence of Pain Management

The prevalence of pain management is significant, as pain is a prevalent and widespread experience that affects individuals of all ages, genders, and backgrounds. Chronic pain, in particular, is a common health condition that can have a profound impact on an individual’s quality of life and overall well-being. Here are some key points regarding the prevalence of pain management:

  1. Chronic Pain: Chronic pain is defined as pain that persists for three months or longer and is estimated to affect millions of people worldwide. According to the Centers for Disease Control and Prevention (CDC), approximately 20.4% of adults in the United States experienced chronic pain in 2019. Chronic pain can result from various underlying conditions, including arthritis, back pain, neuropathy, fibromyalgia, and other musculoskeletal disorders.

Prescription Requirement and Professional Guidance

  • Strictly Prescription-Based: Access to M367 pills is strictly regulated, emphasizing the need for a healthcare provider’s prescription. This regulatory approach ensures that the medication is administered under the supervision of a qualified professional.

  • Professional Instructions: To optimize the benefits of M367 pills and mitigate potential risks, it is imperative to adhere closely to the instructions provided by your healthcare provider. The high dose of the opioid component necessitates careful and cautious usage.

How Does M367 Work in the Brain and Body?

The M367 pill is an oval white pill with the imprint “M367” and contains a combination of two medications: 325 mg of acetaminophen and 10 mg of hydrocodone bitartrate. Acetaminophen is a pain reliever and fever reducer, while hydrocodone is an opioid analgesic. The combination is commonly prescribed for the management of moderate to severe pain.

Here’s how the components of the M367 pill work in the brain and body:

  1. Acetaminophen (Tylenol):

    • Mechanism: Acetaminophen is believed to reduce pain and fever by inhibiting an enzyme called cyclooxygenase (COX) in the brain. Unlike nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen has limited anti-inflammatory effects.
  2. Hydrocodone:

    • Mechanism: Hydrocodone is an opioid analgesic that works by binding to specific receptors called opioid receptors in the brain and spinal cord. These receptors are part of the endogenous pain control system.
    • Effects: Hydrocodone activates mu-opioid receptors, leading to a reduction in the perception of pain. It can also produce a sense of euphoria and sedation.

The combination of acetaminophen and hydrocodone provides a synergistic effect, enhancing pain relief. It’s important to note that opioids, including hydrocodone, carry the risk of dependence, addiction, and other adverse effects. Therefore, these medications should be used under the supervision of a healthcare professional, and the prescribed dosage and duration should be strictly followed.

Effects of M367 Pill on the Body

The M367 pill is a prescription medication containing a combination of two active ingredients: hydrocodone bitartrate (a semi-synthetic opioid analgesic) and acetaminophen (a non-opioid pain reliever). It is commonly prescribed for the management of moderate to moderately severe pain. Here are the effects of the M367 pill on the body:

  1. Pain Relief: The primary effect of the M367 pill is pain relief. Hydrocodone binds to opioid receptors in the brain and spinal cord, altering the perception of pain and providing analgesia. Acetaminophen also contributes to pain relief through mechanisms that are not fully understood but may involve inhibition of prostaglandin synthesis.

  2. Sedation and Drowsiness: Hydrocodone, being an opioid, can cause central nervous system depression, leading to sedation and drowsiness. This effect may impair a person’s ability to perform tasks requiring alertness, such as driving or operating machinery.

  3. Euphoria and Relaxation: Opioid medications like hydrocodone have the potential to produce feelings of euphoria, relaxation, and well-being in some individuals. This effect contributes to the risk of misuse, abuse, and addiction associated with opioids.

  4. Respiratory Depression: One of the most significant risks associated with opioid medications is respiratory depression, where breathing becomes slow and shallow. In high doses or when combined with other central nervous system depressants like alcohol or benzodiazepines, the M367 pill can suppress respiration to dangerous levels, leading to respiratory arrest and death.

  5. Constipation: Opioid medications commonly cause constipation by slowing down gastrointestinal motility. This side effect can be bothersome for many individuals and may require additional treatment or lifestyle modifications to manage.

  6. Nausea and Vomiting: Some individuals may experience nausea and vomiting as side effects of the M367 pill, particularly when first starting the medication or when taking higher doses.

  7. Liver Toxicity: The acetaminophen component of the M367 pill can cause liver damage if taken in high doses or for long periods. It’s essential to adhere to the recommended dosage and avoid combining the M367 pill with other acetaminophen-containing medications to prevent liver toxicity.

  8. Tolerance and Dependence: Prolonged use of the M367 pill can lead to tolerance, where higher doses are needed to achieve the same effect. Additionally, regular use can result in physical dependence, where the body adapts to the presence of the medication and experiences withdrawal symptoms when it is discontinued.

It’s crucial to take the M367 pill exactly as prescribed by a healthcare professional and to be aware of the potential side effects and risks associated with its use. If you experience any concerning symptoms while taking the M367 pill, it’s important to seek medical attention promptly. Additionally, healthcare providers can provide guidance and support for managing pain effectively while minimizing the risks associated with opioid medications.

Understanding the Risk of Hydrocodone-Acetaminophen

Hydrocodone and acetaminophen, the dynamic duo encapsulated in medications such as M367, emerge as powerful allies in the battle against pain. While their efficacy in alleviating discomfort is undeniable, it is crucial to delve into the intricate facets of their usage, potential risks, and the imperative role of healthcare provider guidance. Among the most alarming risks is dose-related respiratory depression, a serious effect of hydrocodone overdose that can significantly slow down breathing, highlighting the importance of adhering to prescribed dosages. Similarly, acetaminophen overdose carries the risk of potentially fatal hepatic necrosis, underscoring the critical nature of liver damage and the necessity for immediate medical attention.

Potential Side Effects and Risks of the M367 Pill

The short-term and long-term side effects of a medication like M367, which typically contains a combination of hydrocodone and acetaminophen, can vary. It’s important to note that individual responses to medications can differ, and the following information provides a general overview:

Short-Term Side Effects:

  1. Pain Relief: Hydrocodone, an opioid, works as a pain reliever by binding to opioid receptors in the brain and spinal cord.

  2. Sedation: Opioids like hydrocodone can cause drowsiness and sedation.

  3. Nausea and Vomiting: Some individuals may experience nausea and vomiting as side effects of opioid medications.

  4. Constipation: Opioids can lead to constipation due to their effects on the gastrointestinal system.

  5. Dizziness: Opioids may cause dizziness or lightheadedness.

Long-Term Side Effects:

  1. Tolerance: Prolonged use of opioids can lead to tolerance, where higher doses are needed to achieve the same pain-relieving effects.

  2. Dependence: With regular use, physical dependence can develop, and abrupt discontinuation may result in withdrawal symptoms such as irritability, insomnia, and flu-like symptoms.

  3. Addiction: Misuse or prolonged use of opioid medications increases the risk of addiction, characterized by compulsive drug-seeking behavior despite negative consequences.

  4. Liver Damage: The acetaminophen component of M367 can cause liver damage if taken in high doses or in individuals with pre-existing liver conditions.

  5. Respiratory Depression: Opioids can suppress the respiratory system, especially in high doses, leading to slowed or shallow breathing.

Other Considerations:

  1. Interaction with Other Medications: Hydrocodone and acetaminophen can interact with other medications, leading to adverse effects or reduced efficacy.

  2. Mental Health Effects: Opioids can impact mood and mental health, and long-term use may be associated with changes in mood or exacerbation of existing mental health conditions.

Due to its opioid component, M367 carries a risk of developing psychological and physical dependence. This potential for dependence is a critical consideration, underscoring the importance of adhering strictly to a healthcare provider’s guidance to mitigate these risks.

Can You Overdose on the M367 Pill?

Yes, it’s possible to overdose on M367, particularly due to the opioid component, hydrocodone. Overdosing on opioids like hydrocodone can lead to serious health complications, including respiratory depression (slowed or stopped breathing), coma, and even death.

The risk of overdose increases if M367 is taken in larger amounts than prescribed, if it’s taken more frequently than directed, or if it’s combined with other substances that depress the central nervous system, such as alcohol or other opioids.

If you suspect that you or someone else may have overdosed on M367 or any medication, it’s crucial to seek emergency medical attention immediately. Prompt treatment can be lifesaving in cases of overdose.


Alcohol Use and M367

Drinking alcohol while taking any medication that contains acetaminophen can increase the risk of liver damage, as both alcohol and acetaminophen can be hard on your liver. Additionally, combining alcohol with hydrocodone can enhance the sedative effects and increase the risk of respiratory depression, which can be dangerous.

It’s important to follow your doctor’s advice and the instructions on the medication label carefully. If you have any questions or concerns about drinking alcohol while taking M367 or any other medication, it’s best to consult with your healthcare provider.


Can You Take the M367 Pill Medication While Pregnant?

When considering medication use during pregnancy, it’s crucial to prioritize both maternal and fetal health. Hydrocodone, the opioid component in the M367 pill, can potentially cross the placenta and affect the developing fetus. Additionally, acetaminophen, while generally considered safe in pregnancy when used as directed, should also be used cautiously and under medical supervision. Therefore, it’s essential to consult a healthcare professional before taking the M367 pill or any medication during pregnancy. They can assess the potential risks and benefits based on individual circumstances and provide guidance on the safest treatment options for managing pain during pregnancy.

M367 Pill Interactions with Medications

The M367 pill is a combination medication containing two active ingredients: hydrocodone bitartrate and acetaminophen. Hydrocodone is an opioid pain reliever, while acetaminophen is a non-opioid pain reliever and fever reducer. Together, they work synergistically to provide pain relief greater than that achieved by either medication alone.

It’s important to be cautious when combining the M367 pill with other medications, as certain drug interactions can occur, potentially leading to adverse effects or reduced effectiveness of either medication. Here are some medications that may interact with the M367 pill:

  1. Other Opioids: Combining the M367 pill with other opioid medications, including prescription pain relievers, cough suppressants, or certain opioid-containing medications for diarrhea, can increase the risk of respiratory depression, sedation, and other opioid-related side effects.

  2. Benzodiazepines and Other Central Nervous System Depressants: Concomitant use of benzodiazepines, sedatives, hypnotics, muscle relaxants, or alcohol with the M367 pill can potentiate central nervous system depression, leading to excessive sedation, respiratory depression, coma, or death.

  3. Monoamine Oxidase Inhibitors (MAOIs): Combining the M367 pill with MAOIs or within 14 days of discontinuing MAOIs can increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by agitation, confusion, hallucinations, rapid heart rate, high blood pressure, fever, sweating, tremors, muscle stiffness, and seizures.

  4. Antidepressants and Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Certain antidepressants and SNRIs can increase the risk of serotonin syndrome when taken with the M367 pill. These include selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), serotonin modulators, and trazodone.

  5. Anticholinergic Medications: Concomitant use of anticholinergic medications with the M367 pill can increase the risk of anticholinergic side effects such as dry mouth, blurred vision, constipation, urinary retention, and confusion.

  6. Medications with Hepatotoxic Potential: Acetaminophen, one of the components of the M367 pill, is metabolized in the liver and can cause liver damage if taken in high doses or with other medications that also have hepatotoxic potential, such as certain antibiotics, antifungals, antiepileptics, and herbal supplements.

It’s important to inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal supplements, to minimize the risk of drug interactions. Your healthcare provider can help determine the safety and appropriateness of combining the M367 pill with other medications based on your individual medical history and needs.

Fake M367 Pills

Fake M367 pills refer to counterfeit or illicitly manufactured pills that resemble the prescription medication with the imprint “M367.” The legitimate M367 pill is a combination medication containing hydrocodone (an opioid pain reliever) and acetaminophen (a non-opioid pain reliever). These pills are typically prescribed to treat moderate to severe pain.

Counterfeit or fake M367 pills may contain unknown substances or incorrect dosages of active ingredients, posing significant health risks to individuals who consume them. Some counterfeit pills may contain dangerous substances such as fentanyl, a potent synthetic opioid that can cause overdose and death even at small doses.

It’s essential to exercise caution when obtaining prescription medications and to only use medications prescribed by a licensed healthcare provider and obtained from a reputable pharmacy. If you suspect that you have encountered fake M367 pills or any other counterfeit medications, it’s crucial to report it to local law enforcement or regulatory authorities immediately.

Responsible Use of the M367 Pill

Responsible use of the M367 pill, which contains a combination of hydrocodone bitartrate and acetaminophen, involves following your healthcare provider’s instructions carefully and taking steps to minimize the risks associated with opioid medications. Here are some guidelines for responsible use:

  1. Follow Prescribing Instructions: Take the M367 pill exactly as prescribed by your healthcare provider. Do not take more medication than prescribed or take it more frequently than directed.

  2. Use for Short-Term Pain Relief: The M367 pill is typically prescribed for short-term pain relief, such as after surgery or for acute injury-related pain. Use it only for the duration recommended by your healthcare provider.

  3. Avoid Alcohol and Other Substances: Do not consume alcohol or other central nervous system depressants while taking the M367 pill, as this can increase the risk of respiratory depression and other serious side effects.

  4. Monitor for Side Effects: Pay attention to any side effects you may experience while taking the M367 pill, such as dizziness, drowsiness, constipation, or nausea. Report any adverse reactions to your healthcare provider promptly.

  5. Prevent Misuse and Diversion: Store the M367 pill securely and out of reach of children, teenagers, and others who may misuse or abuse it. Do not share your medication with others, even if they have similar symptoms.

  6. Avoid Driving and Operating Machinery: The M367 pill can cause drowsiness and impair your ability to drive or operate machinery. Avoid these activities until you know how the medication affects you.

  7. Disposal of Unused Medication: Dispose of any unused or expired M367 pills safely to prevent accidental ingestion or misuse. Follow any specific disposal instructions provided by your pharmacist or healthcare provider.

  8. Seek Help for Dependence or Addiction: If you find that you are developing a dependence on the M367 pill or are concerned about potential addiction, seek help from your healthcare provider or a substance abuse treatment professional. There are resources and treatment options available to help manage opioid dependence and addiction.

It’s essential to have open and honest communication with your healthcare provider about your pain management needs and any concerns you may have about opioid medications like the M367 pill. They can provide guidance, monitor your progress, and adjust your treatment plan as needed to ensure safe and effective pain relief.

M367 Pill Opioid Warning

The M367 pill is a combination medication containing hydrocodone bitartrate and acetaminophen. Hydrocodone is an opioid pain medication, while acetaminophen is a non-opioid pain reliever and fever reducer. Due to the presence of hydrocodone, the M367 pill is classified as an opioid medication.

It’s important to note that opioids, including hydrocodone, carry significant risks, especially when used improperly or without a prescription. Here are some important points to consider regarding the use of the M367 pill:

  1. Risk of Addiction: Opioid medications have the potential for abuse, dependence, and addiction. Misuse or abuse of opioids, such as taking higher doses than prescribed or using them for non-medical purposes, can lead to addiction and other serious consequences.

    One of the most dangerous effects of hydrocodone overdose is dose-related respiratory depression, which can severely slow down breathing, preventing adequate oxygen exchange and leading to serious complications that require immediate medical treatment.

  2. Risk of Overdose: Opioid overdose is a serious and potentially life-threatening complication of opioid use. Taking too much of the M367 pill or combining it with other substances, such as alcohol or benzodiazepines, can increase the risk of overdose.

  3. Withdrawal Symptoms: Prolonged use of opioids can lead to physical dependence, which may result in withdrawal symptoms if the medication is suddenly discontinued. Symptoms of opioid withdrawal may include nausea, vomiting, diarrhea, sweating, anxiety, and flu-like symptoms.

  4. Neonatal Opioid Withdrawal Syndrome (NOWS): If opioids are used during pregnancy, there is a risk of neonatal opioid withdrawal syndrome (NOWS) in the newborn baby. NOWS occurs when a baby experiences withdrawal symptoms after birth due to exposure to opioids in utero.

  5. Respiratory Depression: Opioids can cause respiratory depression, which is characterized by slowed or shallow breathing. This can be particularly dangerous in individuals with respiratory conditions or when opioids are combined with other central nervous system depressants.

  6. Other Risks: Opioid use may be associated with other risks, including constipation, dizziness, sedation, and impaired cognitive function.

Opiate Addiction Treatment

What is Opiate Addiction?

Opiate addiction, also known as opioid use disorder (OUD), is characterized by the compulsive use of opioid drugs, leading to negative consequences on health, relationships, and daily functioning. Addiction often begins with a doctor’s prescription, and users may escalate dosages to maintain the desired effects. Full addiction develops when users can no longer quit due to cravings.

Prevalence of Opiate Addiction

According to the NIH OUD (Opiate Use Disorder) can range from dependence on opioids to addiction. OUD affects over 16 million people worldwide and over 2.1 million in the United States. Strikingly, there are as many patients using opioids regularly as there are patients diagnosed with obsessive-compulsive disorder, psoriatic arthritis, and epilepsy in the United States. More than 120,000 deaths worldwide every year are attributed to opioids.

Opiate Addiction Treatment Options

Opiate addiction is a complex condition that requires a multifaceted approach to address its physical, psychological, and social aspects. Here is a detailed overview of various treatment options available for individuals struggling with opiate addiction:

  1. Detoxification (Detox):

    • Description: Detoxification is the initial phase of treatment aimed at safely and gradually removing opiates from the body.
    • Key Points:
      • Medically supervised detox helps manage withdrawal symptoms.
      • Tapering off opiates may be utilized to reduce the intensity of withdrawal.
      • Detox alone is not sufficient for long-term recovery.
  2. Medication-Assisted Treatment (MAT):

    • Description: MAT combines medications with counseling and behavioral therapies to address opiate addiction.
    • Key Medications:
      • Methadone: Reduces cravings and withdrawal symptoms.
      • Buprenorphine: Eases withdrawal and cravings, with lower risk of misuse.
      • Naltrexone: Blocks opiate effects, reducing cravings.
    • Benefits:
      • Helps prevent relapse.
      • Supports long-term recovery.
      • Reduces withdrawal discomfort.
  3. Inpatient Rehabilitation (Residential Treatment):

    • Description: Inpatient rehab involves staying in a residential facility for a specified duration.
    • Key Features:
      • 24/7 medical supervision and support.
      • Intensive therapy and counseling.
      • Structured environment conducive to recovery.
    • Duration: Typically 30 to 90 days, depending on individual needs.
  4. Outpatient Rehabilitation:

    • Description: Outpatient programs provide treatment without requiring residential stays.
    • Key Features:
      • Allows individuals to maintain daily routines.
      • Regular counseling sessions.
      • Flexibility in scheduling.
    • Intensity: Varies from several hours a week to daily sessions.
  5. Cognitive-Behavioral Therapy (CBT):

    • Description: CBT is a widely used therapeutic approach that addresses thoughts, behaviors, and emotions associated with addiction.
    • Key Components:
      • Identifying and challenging negative thought patterns.
      • Developing coping strategies.
      • Enhancing problem-solving skills.
    • Benefits:
      • Helps change addictive behaviors.
      • Addresses underlying issues contributing to addiction.
  6. Support Groups:

    • Description: Peer support groups provide a sense of community and understanding among individuals in recovery.
    • Examples:
      • Narcotics Anonymous (NA).
      • SMART Recovery.
      • Alcoholics Anonymous (AA) for those with dual diagnoses.
    • Benefits:
      • Shared experiences and insights.
      • Accountability and encouragement.
      • Building a sober network.
  7. Family Therapy:

    • Description: Involves the family in the recovery process to improve communication and support.
    • Objectives:
      • Resolving conflicts.
      • Rebuilding trust.
      • Enhancing family dynamics.
    • Benefits:
      • Addresses family-related stressors.
      • Establishes a supportive environment.
  8. Holistic Therapies:

    • Description: Integrates complementary therapies to support overall well-being.
    • Examples:
      • Yoga and meditation.
      • Art or music therapy.
      • Acupuncture and massage.
    • Benefits:
      • Stress reduction.
      • Improved emotional regulation.
      • Enhanced physical and mental health.
  9. Aftercare and Continuing Support:

    • Description: Ongoing support and resources post-treatment to maintain recovery.
    • Components:
      • Follow-up counseling.
      • Support group participation.
      • Alumni programs.
    • Importance:
      • Reduces the risk of relapse.
      • Sustains motivation for long-term recovery.

Does Insurance Cover Opiate Addiction Treatment?

Yes, many insurance plans cover opiate addiction treatment as part of their behavioral health services. However, the extent of coverage can vary based on factors such as the specific insurance plan, in-network or out-of-network providers, and the level of care needed. Here are key points to consider regarding insurance coverage for opiate addiction treatment:

  1. Type of Insurance Plan:

    • Different types of insurance plans, such as private insurance, Medicaid, or Medicare, may have varying levels of coverage for opiate addiction treatment.
  2. In-Network vs. Out-of-Network Providers:

    • Insurance plans often have a network of preferred providers. In-network opiate addiction treatment facilities or providers are generally covered at a higher rate than out-of-network providers.
  3. Verification of Benefits:

    • It is crucial to contact the insurance provider and verify the specific terms of coverage for opiate addiction treatment. This includes checking details such as copayments, deductibles, and any out-of-pocket expenses.
  4. Medical Necessity and Preauthorization:

    • Insurance coverage for opiate addiction treatment may be contingent on a determination of medical necessity. Preauthorization or approval from the insurance company may be required before entering a treatment program.
  5. Level of Care:

    • Different levels of addiction treatment, such as inpatient, outpatient, or detoxification services, may have different coverage considerations. Some insurance plans may cover certain levels of care more comprehensively.
  6. Length of Treatment:

    • Insurance coverage may be influenced by the length of the opiate addiction treatment program. Some plans may have limitations on the number of days covered, while others may provide more extensive coverage for longer durations.
  7. Parity Laws:

    • Mental Health Parity and Addiction Equity Act (MHPAEA) in the United States requires insurance plans to offer coverage for substance use disorder services, including opiate addiction treatment, at levels comparable to medical and surgical coverage.
  8. Crisis or Emergency Situations:

    • In cases of immediate need or crisis, insurance plans may cover opiate addiction treatment as part of emergency services. However, it is essential to follow up with the insurance provider for ongoing coverage considerations.
  9. Appeals Process:

    • If an insurance claim for opiate addiction treatment is denied, individuals have the right to appeal the decision. The appeals process allows for a review of the denial, and successful appeals can result in coverage being granted.
  10. Out-of-Pocket Expenses:

    • Even with insurance coverage, individuals may still have out-of-pocket expenses, such as copayments or coinsurance. Understanding these costs is essential for financial planning.

It is advisable for individuals seeking opiate addiction treatment to work closely with their insurance provider and the treatment facility’s admissions team to understand the specific terms of coverage. This collaboration helps individuals make informed decisions about treatment options and navigate the financial aspects of addiction care. Additionally, seeking assistance from the treatment facility’s insurance coordinator can provide valuable support in verifying benefits and understanding the insurance process.

Common Insurance Plans Used for Addiction and Mental Health Treatment

Common types of insurance plans used for addiction and mental health treatment include:

  1. Preferred Provider Organization (PPO):

    • PPO plans offer flexibility in choosing healthcare providers, allowing individuals to visit both in-network and out-of-network providers without a referral. PPO plans typically cover a portion of the cost for addiction and mental health rehab services, but out-of-pocket expenses may be higher when using out-of-network providers.
  2. Health Maintenance Organization (HMO):

    • HMO plans require individuals to choose a primary care physician (PCP) who coordinates their care and provides referrals to specialists, including addiction and mental health treatment providers. HMO plans often have lower out-of-pocket costs but may limit coverage to in-network providers, except in emergencies.
  3. Exclusive Provider Organization (EPO):

    • EPO plans combine aspects of both PPO and HMO plans, offering a network of preferred providers for individuals to choose from. While EPO plans do not require a PCP or referrals for specialists, coverage is typically limited to in-network providers, except in emergencies.
  4. Point of Service (POS):

    • POS plans offer individuals the option to receive care from both in-network and out-of-network providers. However, using out-of-network providers may result in higher out-of-pocket costs, and individuals may need a referral from their PCP to see specialists, including addiction and mental health treatment providers.

These insurance plans may vary in terms of coverage, network providers, cost-sharing requirements (e.g., copayments, coinsurance, deductibles), and authorization requirements for addiction and mental health rehab services. It’s essential for individuals to review their insurance plan documents, understand their coverage details, and verify network providers before seeking treatment. Additionally, individuals may need to obtain preauthorization or prior approval for certain rehab services to ensure coverage and minimize out-of-pocket expenses.


In the journey toward pain relief, navigating the complexities of hydrocodone-based medications demands vigilance and informed decision-making. While these opioid analgesics offer invaluable respite from pain, they also harbor the potential for adverse effects, addiction, and overdose. Hence, seeking immediate medical attention for severe pain, adverse reactions, or suspected overdose is imperative. Furthermore, healthcare providers play a pivotal role in facilitating safe usage, from prescribing appropriate doses to monitoring for signs of respiratory depression or dependence. By adopting a comprehensive approach that integrates medication-assisted treatment, withdrawal management, and psychological support, individuals can embark on a path toward recovery while minimizing the risk of adverse outcomes. Remember, when it comes to hydrocodone medications, knowledge is power, and proactive engagement with healthcare professionals can pave the way for safer pain management and improved quality of life.


FAQs on the M367 Pill

What should I do if I miss a dose of the M367 pill?

If you miss a dose of the M367 pill, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Is it safe to take the M367 pill during pregnancy or while breastfeeding?

The M367 pill should be used with caution during pregnancy, as it may cause harm to the unborn baby. It should only be used if the potential benefits outweigh the risks. It is not recommended to take the M367 pill while breastfeeding, as it may pass into breast milk and cause harm to the nursing infant.

Can I Operate Machinery on the M67 Pill?

It’s not recommended to operate machinery while taking the M367 pill or any medication containing hydrocodone and acetaminophen, such as Vicodin. These medications can cause drowsiness, dizziness, and impaired cognitive function, which may affect your ability to operate machinery safely.

What should I do if I have questions or concerns about the M367 pill?

If you have any questions or concerns about the M367 pill, including its uses, side effects, or interactions with other medications, consult your healthcare provider or pharmacist for personalized advice and guidance. They can provide information specific to your individual needs and circumstances.

What should I do if I experience severe side effects from the M367 pill?

If you experience severe side effects from the M367 pill, such as difficulty breathing, chest pain, rapid heartbeat, or signs of an allergic reaction (e.g., rash, swelling, difficulty swallowing), seek immediate medical attention or call emergency services. These may be signs of a serious adverse reaction that requires prompt treatment.

Can I crush or chew the M367 pill?

No, the M367 pill should be swallowed whole with a full glass of water. Crushing, chewing, or breaking the pill can release the medication too quickly, increasing the risk of adverse effects, including overdose.

Seeking Treatment? We Can Help!

At California Prime Recovery, as an in-network provider we work with most insurance plans, such as:

If you or a loved one are struggling with mental health challenges or substance abuse, reach out to California Prime Recovery today. Our team of compassionate professionals is here to support your journey towards lasting well-being. Give us a call at 866-208-2390

Take the first step towards a healthier, addiction-free life today.

Also, check out our blogs posted weekly on Medium.

Frequently Asked Questions

M367 pills are prescribed to manage moderate to severe pain resulting from various conditions, injuries, or surgical procedures. They contain a combination of hydrocodone, an opioid painkiller, and acetaminophen, a non-narcotic pain reliever.

Possible side effects of M367 pills may include drowsiness, nausea, constipation, dizziness, dry mouth, itching, confusion, and in rare cases, respiratory depression. It’s essential to consult a healthcare provider if you experience severe or persistent side effects.

Yes, prolonged use of hydrocodone-acetaminophen medications like M367 can lead to tolerance, dependence, and addiction. It’s crucial to use these medications strictly as prescribed by a healthcare provider to minimize the risk.

If you suspect a hydrocodone overdose, characterized by symptoms like slowed heart rate, unconsciousness, or impaired speech, seek immediate medical attention. Overdoses can be life-threatening, and prompt treatment is essential.

California Prime Recovery offers outpatient programs, including partial hospitalization and intensive outpatient programs, to support individuals struggling with addiction to medications like M367. Our comprehensive approach includes therapy, medication-assisted treatment, and aftercare support. Reach out to us at 866-208-2390 or text us at 949-749-3026 to take the first step towards recovery.

Come work with us

Get Help Now

Admission Coordinators are available 24/7.
Take Control Of Your Life and Call Now.